Chemical shift-based water/fat separation: comparison of fitting models
نویسندگان
چکیده
INTRODUCTION Quantitative water/fat separation in MRI requires careful modeling of the acquired signal. Multiple signal models have been proposed in recent years, but their relative performance has not yet been established. This abstract presents a comparative study of 12 signal models for water/fat separation. The models were selected according to three criteria: magnitude or complex fitting [1-4], single-peak or multi-peak fat spectrum [2,5], and modeling of T2* (or R2*=1/T2*) decay [2,6]. The study uses theoretical Cramer-Rao Lower Bound (CRLB) results, simulation results, phantom and in vivo data. Comparisons are based on the bias and standard deviation of fat amplitude and fat fraction estimates.
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